Can i stop taking paxlovid if it makes me sick - I called the advice nurse and she said there's something called "Paxlovid Rebound" in which the Covid symptoms come back stronger than ever after stopping the med.

 
Yes, the bitter metallic taste is nauseating, but I’ll <b>take</b> it over the inability to swallow food since last Saturday due to major throat pain, which finally subsided this morning. . Can i stop taking paxlovid if it makes me sick

timed out waiting for odj blob or connectivity msi true color download windows 11. Paxlovid, the antiviral drug designed to prevent hospitalization and death stemming from COVID-19 illness, is often prescribed to those impacted by a SARS-CoV-2 infection. Find Drug Warehouse stock photos and editorial news pictures from Getty Images. com Suzanne Hamner In the first of the three part series, Pfizer's PAXLOVID May Prove Dangerous, Buyer Beware, a brief look was taken at the Food and Drug Administration's Emergency Use Authorization letter, what PAXLOVID is, and some issues surrounding the regime. Pfizer made the drug to treat mild to. And during an attack, it can help stop the pain signals, swelling of blood vessels, and. A combination. clay-colored stools. Take Paxlovid exactly as prescribed. Dan S. 8 Ogo 2022. 23 Mei 2022. clion this file does not belong to any project target how to use dampyo calculator. Califf told. Pfizer said it would stop enrolling. Biden touted its effectiveness at his 2020 State of the Union address. Choose a language:. “For high-risk unvaccinated persons, Paxlovid is still the most effective antiviral therapy when started within five days of symptom onset,” Dr. 1 bed student flats. A healthy diet including olive oil, fruits and vegetables, nuts and beans, and whole grains has been proven to improve thinking, memory. light-colored stools. So can “continuing to be a little bit careful,” Rupp says. · Taken for less than 1 month · March 28, 2022. If you miss a dose of PAXLOVID within 8 hours of the time it is usually taken, take it as soon as you remember. Can I spread COVID-19 if I have COVID-19 rebound?. Log In My Account vv. Who should take Paxlovid? Paxlovid is for people age 12 and older, with mild to moderate cases of COVID-19, who are at high risk for developing severe COVID. Why should I take COVID treatment, especially if my symptoms are mild? Treatment can prevent you from getting very sick. My initial symptoms included a high resting heart rate when I tested positive of 4/13/22. · Taken for less than 1 month · March 28, 2022. Symptoms of an allergic reaction include: hives; trouble swallowing or breathing;. “Most likely, people who are at high risk of COVID complications would be more vulnerable to. The FDA has authorized antiviral medications to treat mild to moderate COVID-19 in people who are more likely to get very sick. Paxlovid, the antiviral COVID-19 medication, is a life-saving treatment. red irritated eyes. I'm a college student so it's all good info for me. There is currently no definitive guidance on whether asymptomatic people should take Paxlovid. Do not stop taking Paxlovid without talking to your healthcare provider, even if you feel better. Paxlovid and drinking alcohol. A course of the treatment is 20 Paxlovid pills and 10 ritonavir pills taken over five days. Antiviral treatments target specific parts of the virus to stop it from multiplying in the body, helping to prevent severe illness and death. Overall: You may have flu-like symptoms including headache, muscle pain, weakness. If you miss a dose by more than 8 hours, skip the missed dose and take the next dose at your regular. Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) have happened in patients taking ritonavir, a medicine in PAXLOVID. But people should stop taking. If you miss a dose of Paxlovid within 8 hours of the time it is usually taken, take it as soon as you remember. The anemia may be hypochromic or predominantly. dark urine. When taken within three to five days of COVID-19 symptoms starting, antiviral drugs like Paxlovid may keep people out of the hospital. Take this medication by mouth with or without food as directed by your doctor, usually once in the morning and once in the evening for 5 days. If you have an allergic reaction such as trouble breathing or rash while taking Nurtec ODT, seek medical help right away. what makes a good foot model; neje master 2s review; used trailer for sale in oklahoma; p3d sale; where is southern skies labrador rescue located; homebrew rf signal generator; lake havasu arrests; kia steering wheel light; tuesday car boot sale near me; rokka no yuusha manga full; https www ebay com bmgt buyerblock; discord airdrop nitro. So, if. what makes a good foot model; neje master 2s review; used trailer for sale in oklahoma; p3d sale; where is southern skies labrador rescue located; homebrew rf signal generator; lake havasu arrests; kia steering wheel light; tuesday car boot sale near me; rokka no yuusha manga full; https www ebay com bmgt buyerblock; discord airdrop nitro. If you miss a dose of Paxlovid within 8 hours of the time it is usually taken, take it as soon as you remember. Do not stop taking Paxlovid before the end of your 5 day course without talking to your doctor first. help to stop a virus from infecting healthy cells that can make you sick. My son, a former preemie who was born at 26 weeks who has cardiac and pulmonary disease, caught COVID. swelling of the mouth, lips, or face. How Many Doses Do you Need if You Take the Pill?. Furthermore, many Americans cannot take Paxlovid, given that nearly half of adults have cardiovascular disease. "Pharmacist prescribing of Paxlovid will take time to. Symptoms of liver problems such as loss of appetite. " Was this helpful? Yes No 90 Report No ER visit! · Taken for less than 1 month · February 1, 2022. Swallow the tablets whole. nausea and vomiting. 's oral antiviral Paxlovid are reporting that their COVID-19 symptoms returned after initially . If you feel worse, or do not feel better after 5 days, contact your healthcare provider. Biden had taken the antiviral medication Paxlovid, which has been associated with. how long do you have to press charges for theft. Some physicians believe all at-risk individuals with asymptomatic COVID should start Paxlovid immediately to prevent the disease from becoming severe. Paxlovid® is an oral medication that recently received emergency use authorization from the U. But the tablets should be swallowed whole. This could be why the bad taste of Paxlovid lasts until the next dose. Paxlovid, the antiviral COVID-19 medication, is a life-saving treatment. 16 Sep 2022. And if these occur, providers would need to discontinue Paxlovid and treat the hypersensitivity symptoms. It’s important to be upfront with any prescriber about the medications you ’re taking , since many may interact with Paxlovid and lead to serious complications. Find Drug Warehouse stock photos and editorial news pictures from Getty Images. But nausea caused by medication used to treat arthritis can be a problem for some patients. In addition to the bad taste, Paxlovid also has other side effects, including diarrhea, elevated blood pressure, and muscle aches. Some pharmacies have store-based clinics with authorized staff that can test, evaluate, prescribe, and dispense Paxlovid. Symptoms of liver problems such as loss of appetite. nausea and vomiting. What will happen if I stop taking it? Do not stop taking Paxlovid before the end of your 5 day If you are taking Paxlovid it's important to use effective contraception (a condom, female condom If you take contraception and Paxlovid makes you vomit or have severe diarrhoea for more than 24. Side effects may include liver problems, resistance to HIV medications. what do onlyfans creators see when you subscribe. Swallow the tablets whole with a drink of water. Feeling sick (nausea). Vaccines can lower your odds of contracting COVID-19, federal data shows. (If it happens to be a pharmacist, you should know they are generally highly. These are severe skin rashes / reactions. “If someone has taken it for months at a substantial dose, when. "Pharmacist prescribing of Paxlovid will take time to. The drug has been shown to cut the risk of hospitalization or death in high-risk people by nearly 90% if it's. Talk to your health practitioner if you get any symptoms of liver problems. I have intestinal issues as it is, and I had my colon removed due to Ulcerative COlitis years ago. But people should stop taking Paxlovid and call a health care provider right away if they experience any of the following signs of an allergic reaction: hives trouble swallowing. After taking Paxlovid , he was "surprised and disappointed" to see he tested positive again, and he had symptoms such as a low fever, achiness, runny nose, and "mild cough. · Taken for less than 1 month · March 28, 2022. Vaccines can lower your odds of contracting COVID-19, federal data shows. Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. The new antiviral medication Paxlovid is almost 90 per cent effective at reducing COVID-19 hospitalisations and deaths. A Paxlovid prescription is typically 30 pills. to make sure the COVID-19 treatments can be safely taken at the same time. I actually feel sicker for 2-6 hours after taking a dose - even in the middle of a meal. Recent studies have shown that if you are taking lithium for Bipolar disorder and stop it suddenly (ie over 1 to 14 days. In addition to the bad taste, Paxlovid also has other side effects, including diarrhea, elevated blood pressure, and muscle aches. Rebounded ugh. Some Americans who take Paxlovid, an antiviral for Covid-19, may see their symptoms rebound following a brief recovery, the Centers for Disease Control. The California researchers concluded that the COVID-19 rebound following a course of Paxlovid treatment is likely due to insufficient drug exposure. Patients take three pills twice a day for five days. Getty Images. However, dysgeusia is a prominent side effect of Paxlovid. Rebound illness can happen any time between 2 and 8 days after completing treatment with Paxlovid. " What is that? People have described it as bitter, sour, metallic. If you stop it then medicine doesn’t have chance to completely eliminate the virus replication in body. India; can a horse recover from founder; misd calendar 2022 a day b day; 1979 dodge sportsman rv manual; how to show what i39m playing on discord mobile;. After looking closely at the drug-drug interactions listed for the new oral COVID-19 drug, Paxlovid, I realized that a large percentage of my patients are taking medications on the list. (But if you take these regularly and drink caffeinated drinks. In a recent. Others argue that Paxlovid only makes an impact in people who are already symptomatic. Select from premium Drug Warehouse of the highest quality. 1 bed student flats. If you're being sick, try small, frequent sips of water to avoid dehydration. · 3 mo. Covid-19 rebound also seems to be more common in people who take Paxlovid compared with those who don’t take the antiviral, although it can happen in either circumstance. · Paxlovid is an oral antiviral pill that can be taken at home to help keep high-risk patients from getting so sick that they need to be hospitalized. I basically eat till i feel full, which is pretty quickly, then make myself have a little more. This includes those with cancer, heart disease,. In a recent. 58% of reviewers reported a positive experience, while 24% reported a negative experience. Rebound turned up in about 1 to 2 percent of participants in Paxlovid's clinical trials, both in people. • Do not take PAXLOVID if you are taking any of these medicines. The pill is one that sick people will take at home before they’re hospitalized. and brain health. Some pharmacies have store-based clinics with authorized staff that can test, evaluate, prescribe, and dispense Paxlovid. Mar 02, 2022 · For COVID-19: “I am on day 3 taking Paxlovid after E R confirmed Covid with PCR test-started med on. · Paxlovid does not prevent COVID-19 if you ’ve been exposed to an infected person, a new study shows, but Rupp says the tried-and-true measures that do lower infection risk shouldn’t go ignored. I actually feel sicker for 2-6 hours after taking a dose - even in the middle of a meal. dark urine. i don’t think stopping taking paxlovid will hurt you in and of itself, but it may hurt your. Paxlovid received emergency use authorization from regulators in late 2021, and quickly became a favorite of the White House. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. Stop taking PAXLOVID and call your healthcare provider right away if you get any of the following symptoms of an allergic reaction: hives; trouble swallowing or breathing; swelling of the mouth, lips, or face; throat tightness; hoarseness; skin rash; Liver Problems. So can “continuing to be a little bit careful,” Rupp says. There are things you can do to help cope with them: Diarrhoea Feeling sick or being sick (nausea or vomiting) Changes in your sense of taste Serious side effects There are no known serious side effects with Paxlovid. jenn pellegrino hair. Paxlovid, the antiviral drug designed to prevent hospitalization and death stemming from COVID-19 illness, is often prescribed to those impacted by a SARS-CoV-2 infection. The fatigue may be from Covid or the lack of sleep, I'm not quite sure. Food and Drug Administration (FDA) to prevent severe COVID-19 infection in high-risk individuals who test positive for the virus. Some physicians believe all at-risk individuals with asymptomatic COVID should start Paxlovid immediately to prevent the disease from becoming severe. What to Do If You Relapse. Pfizer has recommended taking another 5-day course of Paxlovid if this happens. bcbs of massachusetts prior authorization forms. Tell your doctor if your. Dan S. After a clinical trial showed that Paxlovid could reduce . If you miss a dose by more than 8 hours, skip the missed dose and take the next dose at your regular. Evusheld contains 2 different antibodies that can help prevent COVID-19. Allergic reactions can happen in people taking PAXLOVID, even after only 1 dose. I was advised to stop taking paxlovid and I started taking Benadryl to help. Stopping the medication too early may allow the virus to continue to grow, which may result in a . Importantly, it doesn’t mean someone has been infected with a new strain of the virus, says. When taken together, they reduce the. If you miss a dose by more than 8 hours, skip the missed dose and take the next dose at your regular time. timed out waiting for odj blob or connectivity msi true color download windows 11. It is taken to decrease the While information so far suggests that most COVID-19 illness is mild, serious illness can happen and Do not stop taking Paxlovid without talking to your healthcare provider, even if you feel better. Among the 1,039 patients who took a five-day course of Paxlovid within five days of developing symptoms, eight, or 0. seadoo no power. Mar 02, 2022 · For COVID-19: “I am on day 3 taking Paxlovid after E R confirmed Covid with PCR test-started med on day 1. Vaccines can lower your odds of contracting COVID-19, federal data shows. About Treatments · Antivirals (e. This is to avoid passing the infection on. black mountain foreclosures. People with a history of hypersensitivity to rimegepant or any of the components of Nurtec ODT should avoid taking Nurtec ODT. When taken within three to five days of COVID-19 symptoms starting, antiviral drugs like Paxlovid may keep people out of the hospital. The new antiviral medication Paxlovid is almost 90 per cent effective at reducing COVID-19 hospitalisations and deaths. It is important to act quickly, because you must begin taking Paxlovid within five days of your first symptom. When I’m actually doing something, it feels like I should. 8 out of 10 from a total of 237 ratings for the treatment of COVID-19. The pill is one that sick people will take at home before. About Paxlovid Who can and cannot take it. If you're being sick, try small, frequent sips of water to avoid dehydration. unless you have a medical condition or are taking any meds that are contraindicated, i wouldn’t stop taking it. According to CBS News, the rebound has been reported to occur two to eight days after taking the Paxlovid dosage. In the past few months. If you are taking Paxlovid it's important to use effective. He then called. But people should stop taking. But people should stop taking. Posted by dmbteach222 @dmbteach222, Jun 3 11:02pm. Paxlovid is made up of two medications: nirmatrelvir, which inhibits the SARS-CoV-2 protein from replicating, and ritonavir, which is best known as an HIV/AIDS treatment that is now used to stop antivirals such as nirmatrelvir from breaking down too quickly so your body can keep fighting the infection. I am curious if anyone has been prescribed Paxlovid to treat their Covid infection? I am vaccinated and boosted but recently contracted covid (postive test on Tuesday, tested on Monday), and my midwife and other doctors on the team are recommending I take this drug to stop the infection from progressing. Patients take all three tablets together, twice daily, for five consecutive days, starting within five days of developing symptoms. The Pfizer and Moderna vaccines contain messenger. That second drug, while it got its start as an antiviral protease inhibitor for HIV therapy, does nothing whatsoever against the coronavirus per se. Paxlovid can stop combined oral contraceptive pills ("the pill") from working properly. for people with mild-to-moderate. If you miss a dose of Paxlovid within 8 hours of the time it is usually taken, take it as soon as you remember. ” But then, one week after his last dose, he got sick once again, with milder cold-like symptoms, and remained sick for about five days. · 3 mo. For me, I regret taking Paxlovid. Jun 29, 2022 · Over the course of the next day, he began to feel "really poorly," and "much worse than in the first go around," he added. This is to avoid passing the infection on. The California researchers concluded that the COVID-19 rebound following a course of Paxlovid treatment is likely due to insufficient drug exposure. The FDA noted these rebound cases in its own analysis of the data from the clinical trials. “People experiencing this may need to try different foods, drinks, or candies to see what can make it. The evidence continues to show that COVID-19 vaccinations and boosters help protect you from getting sick or severely ill with COVID-19. Allergic reactions can happen in people taking PAXLOVID, even after only 1 dose. Do not stop it. People in the study had one or. Stop taking PAXLOVID and call your healthcare provider right away if you get any of the following symptoms of an allergic reaction: hives; trouble swallowing or breathing; swelling of the mouth, lips, or face; throat tightness; hoarseness; skin rash; Liver Problems. This causes. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. After taking Paxlovid , he was “surprised and disappointed” to see he tested positive again, and he had symptoms such as a low fever, achiness, runny nose, and “mild cough. “Paxlovid is usually very well-tolerated,” he says. Do not stop taking Paxlovid without talking to your healthcare provider, even if you feel better. · Paxlovid is an oral antiviral pill that can be taken at home to help keep high-risk patients from getting so sick that they need to be hospitalized. inhibits a SARS-CoV-2 protein to stop the virus from replicating, . jobs in lake havasu az

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Paxlovid does not prevent COVID-19 if you've been exposed to an infected person, a new study shows, but Rupp says the tried-and-true measures that do lower infection risk shouldn't go ignored. . Can i stop taking paxlovid if it makes me sick

Among the 1,039 patients who took a five-day course of Paxlovid within five days of developing symptoms, eight, or 0. I actually feel sicker for 2-6 hours after taking a dose - even in the middle of a meal. A seemingly rapid response, but admittedly an N of 1. and brain health. Paxlovid is the umbrella name for the combination of the Pfizer protease inhibitor. You'll need a prescription to get them, and you have to start taking them . Paxlovid, the antiviral COVID-19 medication, is a life-saving treatment. In the past few months. If COVID-19 symptoms recur following Paxlovid treatment, they're typically mild and resolve in about three days, the CDC said. The Pfizer and Moderna vaccines contain messenger. country thunder chicago; kia connect subscribe; can you exercise after. “Those benefits are still seen with Paxlovid, whether you have rebound symptoms or not,” he said. May 31, 2022 · Here’s What Scientists Know About Paxlovid Rebound. And during an attack, it can help stop the pain signals, swelling of blood vessels, and. Johannes recommended using mints and gum to help distract from any unpleasant flavor. Paxlovid is an antiviral medicine that works by stopping the virus that causes coronavirus (COVID-19) from growing and spreading in the body. I thought about discontinuing Paxlovid, due to the side effects. Serious side effects of Paxlovid include hives, difficulty breathing, swelling of your face, lips, tongue, or throat; severe dizziness, and. Don’t delay: Treatment must be started within days after you first develop symptoms to be effective. It's given through a needle in the skin (intravenously). Symptoms of liver problems such as loss of appetite. High blood pressure. 26 Mei 2022. May 20, 2022 · Your doctor will also need to review with you all. “People experiencing this may need to try different foods, drinks, or candies to see what can make it. Around two weeks ago, one of my long-term, very stable patients with HIV called me saying she’d just been diagnosed with COVID-19. Jan 17, 2022 · Fortunately, there is no short-term risk to stopping these drugs, so my advice to patients will be to stop taking the four statins as soon as COVID-19 is diagnosed and resume them 7 days after. A seemingly rapid response, but admittedly an N of 1. A study of more than 2,200 patients at high risk from Covid-19 showed that Paxlovid cut the risk of hospitalization or death by 89% compared with a placebo. And during an attack, it can help stop the pain signals, swelling of blood vessels, and. 1 to 1. What kinds of conditions you can include in yours is very state-specific, so be sure to consult with your attorney. Stop taking PAXLOVID and call your healthcare provider right away if you get any of the following symptoms of an allergic reaction: hives; trouble swallowing or breathing; swelling of the mouth, lips, or face; throat tightness; hoarseness; skin rash; Liver Problems. Do not stop taking PAXLOVID without talking to your healthcare provider, even if. The FDA has authorized antiviral medications to treat mild to moderate COVID-19 in people who are more likely to get very sick. (In my case, I have an outstanding internist, who not only provided a Paxlovid prescription but also advised me to stop taking my statin while I was on it. ” But then, one week after his last dose, he got sick once again, with milder cold-like symptoms, and remained sick for about five days. Paxlovid is available by prescription only and can be taken at home. Paxlovid is an oral antiviral treatment that can be taken at home to prevent high-risk COVID-19 patients from becoming sick enough to be hospitalized. According to Health Canada, Paxlovid is an antiviral medication in pill form that works best to limit the severity of COVID-19 when taken . The five-day course of prescription. 3 doses in and I have horrible diarrhea. " However, he clarified that the drug is still effective. public health agency warned symptoms can recur after people complete a course of the drug, and they should then isolate a second time. fe; vi; zh; np; mx; tx; cg; yb; jx; en; xg; rh; lz. Posted by dmbteach222 @dmbteach222, Jun 3 11:02pm. 58% of reviewers reported a positive experience, while 24% reported a negative experience. · 3 mo. PAXLOVID is made up of two different tablets: pink tablets containing nirmatrelvir and white tablets containing ritonavir. · Some of the common cardiac medications that you cannot take with Paxlovid include amiodarone, flecainide, Plavix, Brilinta, and some statins. You may need a different dose. Paxlovid has an average rating of 6. 58% of reviewers reported a positive experience, while 24% reported a negative experience. I have a horrible disgusting acidic metallic taste in mouth & an upset tummy. Health care providers should consider treatment. For diarrhea, take probiotics. I have intestinal issues as it is, and I had my colon removed due to Ulcerative COlitis years ago. Covid-19 rebound also seems to be more common in people who take Paxlovid compared with those who don’t take the antiviral, although it can happen in either circumstance. You must take both for PAXLOVID to work. No, Paxlovid does not appear to be able to prevent infection, at least the way it has been tested so far. Aug 02, 2022 · clay-colored stools. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. Jul 20, 2022 · Take Paxlovid with or without food. People at. Other medications, such as carbamazepine (Tegretol) and rifampin (Rifadin), cause your body to get rid of Paxlovid (nirmatrelvir / ritonavir) faster than normal if taken together. But people should stop taking Paxlovid and call a health care provider right away if they experience any of the following signs of an allergic reaction: hives trouble swallowing. Drug interactions. By his 4th day sick, his blood oxygenation was down to 89 and he was miserable with a cough and fevers. · Paxlovid is most helpful for people with mild COVID symptoms who are at high risk of developing severe disease. If you miss a dose of Paxlovid within 8 hours of the time it is usually taken, take it as soon as you remember. A civil injunction is the divorce court’s version of a personal protection order. Based on this information, I think it makes sense to monitor heart rate and blood pressure twice daily on any cardiac patient taking Paxlovid and adjust medications accordingly. Together, they reduce the ability of SARS-CoV-2, the virus that causes COVID, to multiply in your body. Paxlovid is an oral antiviral pill that can be taken at home to help keep high-risk patients from getting so sick that they need to be hospitalized. Give your brain the best chance to heal by avoiding substances which can adversely affect it. 5 in the U. Apr 24. fq ov. Paxlovid no rebound! Just wanted to share I’m 11 days after finishing my paxlovid dose, 2. Sort by. Some pharmacies have store-based clinics with authorized staff that can test, evaluate, prescribe, and dispense Paxlovid. Among the 1,039 patients who took a five-day course of Paxlovid within five days of developing symptoms, eight, or 0. So can “continuing to be a little bit careful,” Rupp says. All events submitted to the community calendar must be located within City limits and open to the general public. Don’t delay: Treatment must be started within days after you first develop symptoms to be effective. But other meds, such as amiodarone, hang around in the body for quite a while, and adding Paxlovid is completely contraindicated. If you miss a dose of Paxlovid within 8 hours of the time it is usually taken, take it as soon as you remember. aita infertility. Paxlovid is an oral antiviral pill that can be taken at home to help keep high-risk patients from getting so sick that they need to be hospitalized. Allergic reactions. When I’m depressed I can’t make decisions because everything feels “wrong. Jun 03, 2022 · Those who experience a reaction are urged to stop taking Paxlovid and call a health care provider. People with certain medical conditions. Dan S. Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) have happened in patients taking ritonavir, a medicine in PAXLOVID. When I’m actually doing something, it feels like I should. The new antiviral medication Paxlovid is almost 90 per cent effective at reducing COVID-19 hospitalisations and deaths. Serious side effects of Paxlovid include hives, difficulty breathing, swelling of your face, lips, tongue, or throat; severe dizziness, and. Oral antivirals are a pill taken by mouth for the treatment of COVID-19 in . Do not chew, break, or crush. Jul 18, 2022 · Most people who take Paxlovid should not experience serious side effects, explains Dr. However, researchers claim four days after finishing the full course of Paxlovid, his symptoms, including a runny nose and sore throat returned for a few more. Like any drug, Paxlovid has side effects, one of the most common being a weird, metallic taste in your mouth. 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